Scientific letter N°20

Reduction with hydride reagents: an overview (Part I)

Our first scientific newsletter was published in September 2008, and 15 years later we are still really happy to share our scientific monitoring with you. For a number of years now, we have also been sharing our work through other means, such as our webinars and bi-monthly posts that you can find on our LinkedIn company page #The Minute Of Chemistry.

In this 20th issue, our Scientific Director Jacques Lebreton uses examples from recent literature, mainly in medicinal chemistry, to review the versatility of hydride donor reducing agents. The latter focuses on a series based on our latest thinking on the use of reagents that we think are generally under-exploited. You can find out more about this topic in our next Webinar, which will be held on 07th December at 3pm and will focus on TosMic “TosMic: a powerful reagent in the synthesis of heterocycles“.

Before you dive into reading this latest issue, here are a few news we wanted to share with you.

In order to expand our range of chemical synthesis services, we have acquired new medium-pressure liquid chromatography purification equipment (BUCHI C-815 Flash Chromatography: 250mL/min 0-50bar with UV detector), which allows us to use kilogram scale silica columns for reliable and reproducible purification of your compounds, while guaranteeing the safety of our chemists. You will also find a portrait of one of them, our project manager for the last 3 years at AtlanChim Pharma: Dr. Thomas Glachet.

Finally, we are pleased to inform you that our website ( has been completely redesigned. You can find our expertise, news and all our scientific letters!

Enjoy your reading!

Aurélie et Héléna

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