Impurities services

Isolation of impurities

From a sample of your mixture or an HPLC analysis, we estimate if we will be able to isolate enough quantity to perform the structural elucidation (about 10 mg). We then prepare a quote for isolation of your impurity with a production time and a cost.

Isolation is accomplished by purification on column chromatography on silica gel (normal phase), by purification by flash or semi preparative chromatography (reverse phase), by preparative CCM …

Structural identification of impurities

NMR analyses (1H, 13C, DEPT, COSY, HMBC, HSQC …), HRMS, IR, RX … should be done to identify the structure of your impurity.

Synthesis of impurities

After structural elucidation, we can prepare a quote for the synthesis of impurity in mg to g scale (FFS or FTE depending on bibliographic study).

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Impurities services

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