Thesis & Post-doc

PhD Defense in 2019: “Utilization of iodonitrene in organic synthesis: application to the synthesis of NH-sulfoximines and 3H-diazirines” (Vincent Reboul, Normandy University, Caen)
Post-Doctoral experience 2019-2020: “Synthesis of pyrrolidine using azomethine ylides” (Jean-François Brière, IDECHEM joint laboratory, Normandy University & ORIL Industrie, Rouen)

Publications

Mechanistic investigation of the NH-sulfoximination of sulfide. Evidence for lambda6-sulfanenitrile intermediates, Chem. Commun. 2017, 53, 2064-2067
Desymmetrization of Hepta-1,6-dien-4-ol by a Highly Stereo­selective Tandem Prins–Ritter Cyclization: Access to New THP Acetamides, Synthesis 2017, 49, 5197-5202
One-Pot Synthesis of Aryl- and Alkyl S-Perfluoroalkylated NH-Sulfoximines from Sulfides, Chem. Eur. J. 2018, 24, 17006-17010
Late-Stage Sulfoximination: Improved Synthesis of the Anticancer Drug Candidate Atuveciclib, Synthesis 2019, 51, 971-975
Terminal Diazirines Enable Reverse Polarization Transfer from 15N2 Singlets, Angew. Chem. Int. Ed. 2019, 58, 11118 – 11124
Iodonitrene in Action: Direct Transformation of Amino Acids into Terminal Diazirines and 15N2-Diazirines and Their Application as Hyperpolarized Markers, J. Am. Chem. Soc. 2019, 141, 13689-13696
A Straightforward Synthesis of N-Substituted Ureas from Primary Amides, Synthesis 2020, 52, 2099-2105
One-Pot Synthesis of Diazirines and 15N2-Diazirines from Ketones, Aldehydes and Derivatives: Development and Mechanistic Insight, Adv. Synth. Catal. 2021, 363, 4390-4398

THOMAS GLACHET

Close Menu