Thèse & Post-doc

2016 - 2019 : « Utilisation de iodonitrène en synthèse organique : Application à la synthèse de NH-sulfoximines et de 3H-diazirines» (Vincent Reboul, Normandie Université, Caen)

2019-2020 : « Synthèse de pyrrolidine avec des ylures d’azométhine» (Jean-François Brière, Laboratoire commun IDECHEM, Normandie Université & ORIL Industrie, Rouen)

Publications

Mechanistic investigation of the NH-sulfoximination of sulfide. Evidence for lambda6-sulfanenitrile intermediates, Chem. Commun. 2017, 53, 2064-2067

Desymmetrization of Hepta-1,6-dien-4-ol by a Highly Stereo­selective Tandem Prins–Ritter Cyclization: Access to New THP Acetamides, Synthesis 2017, 49, 5197-5202

One-Pot Synthesis of Aryl- and Alkyl S-Perfluoroalkylated NH-Sulfoximines from Sulfides, Chem. Eur. J. 2018, 24, 17006-17010

Late-Stage Sulfoximination: Improved Synthesis of the Anticancer Drug Candidate Atuveciclib, Synthesis 2019, 51, 971-975

Terminal Diazirines Enable Reverse Polarization Transfer from 15N2 Singlets, Angew. Chem. Int. Ed. 2019, 58, 11118 – 11124

Iodonitrene in Action: Direct Transformation of Amino Acids into Terminal Diazirines and 15N2-Diazirines and Their Application as Hyperpolarized Markers, J. Am. Chem. Soc. 2019, 141, 13689-13696

A Straightforward Synthesis of N-Substituted Ureas from Primary Amides, Synthesis 2020, 52, 2099-2105

One-Pot Synthesis of Diazirines and 15N2-Diazirines from Ketones, Aldehydes and Derivatives: Development and Mechanistic Insight, Adv. Synth. Catal. 2021, 363, 4390-4398